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Fig. 1 | The Journal of Headache and Pain

Fig. 1

From: Contributions of p38 and ERK to the antinociceptive effects of TGF-β1 in chronic constriction injury-induced neuropathic rats

Fig. 1

Time course of anti-hyperalgesic effects of transforming growth factor-β1 (TGF-β1) in rats with chronic constriction injury (CCI) at 14 d post-surgery. The x-axis represents the time (h) from intrathecal (i.t.) injection of vehicle or TGF-β1 (5 ng), and the y-axis represents the percentage of the maximum possible effect (%MPE) for anti-hyperalgesia. TGF-β1 significantly attenuated CCI-induced thermal hyperalgesia in rats at 14 d post-surgery. Each point shows the mean ± standard error of the mean (SEM) from six rats per group. *P < 0.05 compared to the CCI plus vehicle group at the same time points

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The Journal of Headache and Pain

ISSN: 1129-2377

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