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Table 2 Detailed data of blood samplings in ECH patients: date and time, concentrations of PACAP-38 and therapyᅟ

From: Release of PACAP-38 in episodic cluster headache patients – an exploratory study

Patients

Date and time of inter-bout sampling

Inter-bout PACAP-38 plasma level (fmol/ml)

Last previous attacks (months ago)

Date and time of ictal sampling

Ictal PACAP-38 plasma level (fmol/ml)

Beginning of bout period (days) and attacks (hours) before the ictal sampling

Applied therapy

ECH-P1

06 June 2010 03:30 pm

22,70

3.0

15 May 2011 07:35 pm

31,00

Since 14 days, 3 h

O 2, Sumariptan

ECH-P3

13 June 2010 01:15 pm

28,80

2.5

27 June 2010 07:55 pm

28,80

Since 2 days, 1.5 h

O 2

ECH-P4

11 July 2010 01:15 pm

20,91

5.0

16 Aug 2010 08:00 am

26,00

Since 7 days, 2.5 h

O 2 , Sumatriptan

ECH-P8

10 Sept 2010 08:30 am

24,40

2.0

15 Oct 2010 02:45 pm

27,30

Since 5 days, 2.5 h

O 2

ECH-P9

19 Sept 2010 10:30 am

25,20

2.5

   

NSAIDs

ECH-P10

28 Nov 2010 01:00 pm

24,50

1.5

   

NSAIDs

ECH-P11

12 Jan 2011 10:00 am

22,20

3.0

   

NSAIDs

ECH-P12

29 Jan 2012 12:30 pm

23,37

3.5

11 Oct 2011 01:20 pm

29,1

Since 4 days, 2.0 h

O 2 , Sumatriptan

ECH-P13

19 Dec 2011 09:00 am

25,06

2.5

   

O 2 , Sumatriptan, NSAIDs

Mean ± SD

 

24.1 ± 2.3

2.8 ± 1.0

 

28.4 ± 1.9

6.4 ± 4.6 days 2.3 ± 0.6 h