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Table 3 Summary of results for IHC for pERK and IL-1β regarding neurons, fibers and satellite glial cells (SGC); intensity scale: “-” no staining, “+/-” very weak staining, “+”-weak staining, “++”-moderate staining, “+++” strong staining

From: KYNA analogue SZR72 modifies CFA-induced dural inflammation- regarding expression of pERK1/2 and IL-1β in the rat trigeminal ganglion

 

pERK 1/2

IL-1β

Groups

Neurons (nucleolei)

Fibers

SGC

Neurons

Fibers

SGC

Pre-treatment SZR72 (dura exposed to CFA)

+

+

+/-

+/-

+

-

Pre-treatment saline (dura exposed to CFA)

+

+

+++

+++

+

-

Repeated treatment SZR72 (dura exposed to CFA)

+

+

++

+/-

+

-

Repeated treatment saline (dura exposed to CFA)

+

+

+++

+++

+

-

Intact control (unoperated)

+

+

+/-

-

+

-