Fig. 1From: KYNA analogue SZR72 modifies CFA-induced dural inflammation- regarding expression of pERK1/2 and IL-1β in the rat trigeminal ganglionpERK1/2 in the trigeminal ganglion. a In fresh animals, pERK1/2 immunoreactivity was detected in a few nuclei of the trigeminal ganglia, including nucleoli, in fresh animals. No immunoreactivity was found in the neuronal cytoplasm. A few SGC were considered as positively stained. b In CFA animals repeated treatment with saline i.p., high-intensity pERK1/2 immunoreactivity was observed in SGCs. c Animals treated with KYNA for 7 days, diminished immunoreactivity to pERK1/2 in SGCBack to article page