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Fig. 1 | The Journal of Headache and Pain

Fig. 1

From: KYNA analogue SZR72 modifies CFA-induced dural inflammation- regarding expression of pERK1/2 and IL-1β in the rat trigeminal ganglion

Fig. 1

pERK1/2 in the trigeminal ganglion. a In fresh animals, pERK1/2 immunoreactivity was detected in a few nuclei of the trigeminal ganglia, including nucleoli, in fresh animals. No immunoreactivity was found in the neuronal cytoplasm. A few SGC were considered as positively stained. b In CFA animals repeated treatment with saline i.p., high-intensity pERK1/2 immunoreactivity was observed in SGCs. c Animals treated with KYNA for 7 days, diminished immunoreactivity to pERK1/2 in SGC

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