Headache: an important factor associated with muscle soreness/pain at the two-year follow-up point among patients with major depressive disorder

Table 3 The correlations of muscle soreness/pain at baseline and two-year follow-up with headache indices, depression, and anxiety at baseline

Time points	Treatment	Number		Neck	Shoulder	Back	Upper limbs	Lower limbs
Baseline	No Tx	155	HI	0.46**	0.45**	0.36**	0.29**	0.37**
	No Tx	155	HF	0.36**	0.36**	0.20*	0.16*	0.16*
	No Tx	155	HADS-D	0.12	0.17*	0.12	0.01	0.08
	No Tx	155	HASD-A	0.26**	0.32**	0.33**	0.17*	0.19*
Two years	No Tx	101	HI	0.13	0.31**	0.21*	0.26**	0.27**
	No Tx	101	HF	0.02	0.21*	0.12	0.15	0.14
	No Tx	101	HADS-D	−0.02	−0.03	−0.04	−0.02	−0.05
	No Tx	101	HASD-A	0.01	0.07	0.06	0.11	0.21*
	Tx	30	HI	0.56**	0.41*	0.45*	0.32	0.39*
	Tx	30	HF	0.42*	0.33	0.31	0.34	0.44*
	Tx	30	HADS-D	0.08	0.03	−0.15	0.03	0.20
	Tx	30	HASD-A	0.22	0.08	−0.02	−0.24	−0.07

HADS-D the depression subscale of the Hospital Anxiety and Depression Scale (HADS), HADS-A the anxiety subscale of the HADS, HI average headache intensity in the past week, HF headache frequency measured by the headache days in the past week, Tx accepted pharmacotherapy in the index follow-up month
*P < 0.05; **P < 0.01

ISSN: 1129-2377