Fig. 2

Pre-administration of VPA reduced the expression of CGRP in jugular blood and the expression of c-Fos in trigeminal nucleus caudalis. a quantitative analysis results of expression of CGRP in different groups. “a”, significantly different from control group, P < 0.05; “b”, significantly different from VPAH group, P < 0.05; “c”, significantly different from NTG group, P < 0.05. b representative images of immunohistochemical staining of c-Fos in different groups, c-Fos positive neurons were stained brown