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Fig. 3 | The Journal of Headache and Pain

Fig. 3

From: Nigrostriatal dopaminergic depletion increases static orofacial allodynia

Fig. 3

Expression of PKCγ in saline-CCI-IoN (a) and 6-OHDA-CCI-IoN (b) animals. Intense PKCγ labeling was observed within the MDH in lamina IIi cells and in scattered cells of lamina III in both animal groups, but the highest staining signal was observed in the 6-OHDA- group (b). c A high magnification showing the intense label within lamina IIi and in cells within lamina III. PKCγ staining intensity analysis (d) showed a significant increase in 6-OHDA injected animals within lamina IIi in both ipsi (P < 0.01) and contralateral (P < 0.05) sides of the MDH. PKCγ positive cell count within lamina III (e) showed a significant increase (P < 0.05) in cell number for 6-OHDA-CCI-IoN compared to saline-CCI-IoN animals. Scale bar represents 100 μm in A-B and 30 μm in C

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