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Table 1 Outcome of the 15 drCCH patients treated with iONS. Patients in grey were explanted due to paraesthesia intolerance or infection

From: Invasive occipital nerve stimulation for refractory chronic cluster headache: what evolution at long-term? Strengths and weaknesses of the method

Patients

Age

CH natural history

CCH duration (years)

Time under ONS (months)

Attacks/day before ONS (mean)

Attacks/day at last follow-up (mean) (Magis Headache 2011)

Attacks/day at very long-term follow-up (mean)

% change in attack frequency

Preventive therapy at time of implantation

Preventive therapy at follow-up

Technical problems

iONS

Satisfaction

1

50

E

9

4

0.29

N/A

N/A

N/A

Verapamil

N/A

Unbearable paresthesias: explanted after 4 months iONS

N/A

Not satisfied because of paresthesias

2

53

E

3

103

4.7

0.43

0.33

−93.00 %

Verapamil Melatonine

Lithium carbonate Verapamil

Empty battery: ×3

ON

Satisfied

3

51

E

7

102

3.84

0

0.1

−97.40 %

Lithium carbonate Verapamil

None

Empty battery: ×4 Lead migration: ×1

ON

Very satisfied

4

37

E

4

53

1.16

0.1

0.33

−71.55 %

Lithium carbonate Verapamil

Lithium carbonate Verapamil

Empty battery: ×2 Delayed infection: explanted

N/A

Very satisfied then explanted

5

57

E

4

38

0.16

0

N/A

N/A

Verapamil

N/A

Delayed infection: explanted

N/A

Not available

6

34

C

6

95

0.16

0

Episodic

Episodic

Lithium carbonate Verapamil

Verapamil Lithium carbonate Topiramate

Empty battery: reluctant to replacement

OFF

Satisfied

7

63

E

5

95

1.00

0

0.17

−83.00 %

Methysergide Lithium carbonate

Lithium carbonate

Empty battery: ×3

ON

Satisfied

8

51

E

3

83

4.00

0

1

−75.00 %

Verapamil Methylprednisolone

None

Empty battery: ×1

OFF

Not satisfied

9

53

C

29

35

1.5

0.16

Episodic

Episodic

Verapamil Lithium carbonate Methysergide

During bouts: GON injection, verapamil, lithium carbonate

Unbearable paresthasias: explanted

N/A

Not satisfied because of paresthesias

10

33

E

5

68

2.00

0

Episodic

Episodic

Verapamil

Verapamil Gabapentine

Empty battery: ×1

ON

Satisfied

11

46

C

2

64

0.57

0.5

0.54

−5.26 %

Verapamil Lithium carbonate Gabapentine Escitalopram

Verapamil Gabapentine

Delayed device infection: explanted and reimplanted

ON

Moderately satisfied

12

34

E

8

na

na

na

N/A

N/A

Methylprednisolone

N/A

Immediate device infection: explanted

N/A

N/A

13

67

C

5

58

3.5

0

1

−71.00 %

Lithium carbonate Verapamil

Lithium carbonate Verapamil

Empty battery: ×1

OFF

Not satisfied

14

55

C

2

57

5.5

0

Episodic

Episodic

Methylprednisolone Methysergide Clomipramine

GON injection Verapamil

Empty battery: ×1

OFF

Not satisfied

15

30

C

14

54

3.00

0

Episodic

Episodic

Methysergide Topiramate Verapamil

GON injection Verapamil Lithium carbonate

Empty battery: ×1 Lead externalization

ON

Not satisfied

  1. E evolved from an episodic to a chronic pattern, C chronic since the onset, N/A not applicable
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The Journal of Headache and Pain

ISSN: 1129-2377

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