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Table 3 Pre- and post-treatment outcomes in OnabotulinumtoxinA 195 U treated group

From: A two years open-label prospective study of OnabotulinumtoxinA 195 U in medication overuse headache: a real-world experience

 

Headache days

Migraine days

Medication intake days

HIT-6

Baseline (1st injection)

22.2 ± 4.9

21.6 ± 4.8

21.0 ± 5.1

67.9 ± 4.2

3 months (2nd injection)

14.1 ± 3.4*

13.5 ± 3.6*

13.8 ± 3.2*

--

6 months (3rd injection)

10.2 ± 2.8*

9.7 ± 2.7*

9.9 ± 1.9*

61 ± 3.9*

9 months (4th injection)

7.4 ± 2.2*

6.9 ± 1.6*

7.0 ± 1.6*

--

12 months (5th injection)

5.7 ± 1.7*

5.4 ± 1.2*

5.6 ± 1.4*

56.8 ± 3.8*

15 months (6th injection)

5.4 ± 1.2*

4.8 ± 1.0*

5.1 ± 1.3*

--

18 months (7th injection)

4.9 ± 1.3*

4.5 ± 1.0*

4.7 ± 1.3*

54 ± 4.6*

21 months (8th injection)

4.4 ± 1.2*

4.1 ± 1.0*

4.2 ± 1.4*

--

24 months

4.1 ± 1.0*

3.8 ± 1.0*

3.7 ± 1.3*

49 ± 6.7*

  1. Data are presented as mean ± standard deviation
  2. *p ≤ 0.05