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Table 2 Baseline pain variables, awareness of parafunctions and diagnoses according to RDC/TMD Axis I in 40 patients with myofascial temporomandibular disorders randomized to treatment with active substance (GRA) or control substance (CTR)

From: Repeated tender point injections of granisetron alleviate chronic myofascial pain - a randomized, controlled, double-blinded trial

 

GRA (n = 20)

CTR (n = 20)

RDC/TMD Axis II

  

Duration of myofascial pain (months)

  

 Mean (SD)

80 (54)

82 (66)

 6-12 months

1

1

 ≥12 months

19

19

Frequency of myofascial pain

  

 Recurrent

5

8

 Persistent

15

12

Current myofascial pain intensity (NRS 0–10)

  

 Median (IQR)

6.0 (4.0)

6.0 (4.0)

Worst myofascial pain intensity last 6 months (NRS 0–10)

  

 Median (IQR)

8.0 (2.0)

8.0 (2.0)

Average myofascial pain intensity last 6 months (NRS 0–10)

  

 Median (IQR)

5.0 (3.0)

6.0 (5.0)

Pain area (AU)

  

 Median (IQR)

5930 (5059)

3861 (13596)

Awareness of clenching/grinding

  

 Daytime

1

2

 Nighttime

2

1

 Both day- and nighttime

15

15

RDC/TMD Axis I

  

 Myofascial pain (Ia)

10

13

 Myofascial pain (Ib)

10

7

Disc displacement with reduction (IIa)

  

 One side

5

5

 Both sides

7

7

Arthralgia (IIIa)

  

 One side

1

0

 Both sides

4

3

Osteoarthrosis (IIIc)

  

 One side

0

1

 Both sides

1

1

  1. GRA Granisetron (Kytril®; 1 mg/mL, Roche, Stockholm, Sweden), CTR control substance (isotonic saline (NaCl); 0.9 mg/mL, Fresenius Kabi, Uppsala, Sweden), RDC/TMD Research Diagnostic Criteria for temporomandibular disorders, SD Standard deviation, IQR Interquartile range (the 75th percentile minus the 25th percentile), NRS Numeric Rating Scale, AU Arbitrary units; There were no significant differences between groups