Table 1 Physiological parameters in animals where Ki for 51Cr-EDTA was determined. Hematocrit in animals treated with CFA was lower than in the vehicle group at 24 h following application to the dura. No other differences regarding measured physiological data were observed between the groups
Vehicle (n = 6) | CFA 2 h (n = 6) | CFA 24 h (n = 5) | CFA 48 h (n = 5) | IS 2 h (n = 6) | IS 24 h (n = 4) | |
|---|---|---|---|---|---|---|
MAP (mmHg) | 98 ± 7 | 88 ± 3 | 87 ± 6 | 105 ± 7 | 85 ± 5 | 104 ± 9 |
Hct (%) | 50 ± 2 | 46 ± 3 | 38 ± 2* | 42 ± 1 | 46 ± 2 | 42 ± 2 |
pCO2 (kPa) | 4.6 ± 0.1 | 4.6 ± 0.1 | 4.7 ± 0.2 | 4.5 ± 0.1 | 4.6 ± 0.1 | 4.8 ± 0.2 |
pO2 (kPa) | 11.5 ± 0.1 | 11.6 ± 0.1 | 11.0 ± 0.2 | 12.7 ± 0.5 | 11.4 ± 0.3 | 11.4 ± 0.5 |
Na+ (mmol) | 136.3 ± 0.6 | 138.0 ± 1.6 | 138.6 ± 1.0 | 137.0 ± 0.5 | 137.0 ± 0.5 | 136.5 ± 0.9 |
K+(mmol) | 4.82 ± 0.39 | 4.65 ± 0.39 | 4.36 ± 0.13 | 4.40 ± 0.13 | 4.57 ± 0.14 | 4.55 ± 0.22 |
pH | 7.50 ± 0.02 | 7.45 ± 0.02 | 7.46 ± 0.02 | 7.46 ± 0.01 | 7.48 ± 0.01 | 7.48 ± 0.01 |