Table 4 Comparison of distribution of genotypes of selected SNP markers between migraine and control group
From: Association of genetic loci for migraine susceptibility in the she people of China
All | ||||||||
|---|---|---|---|---|---|---|---|---|
Migraine (n = 300) | Control (n = 300) | Univariate analysis | Multivariate analysisa | |||||
SNP | n | % | n | % | OR (95 % CI) | P value | ORa (95 % CI) | P value |
rs4379368 | ||||||||
CC | 43 | 14.3 | 70 | 23.3 | 0.56 (0.34, 0.90) | 0.016 | 0.52 (0.32, 0.85) | 0.008 |
CT | 162 | 54 | 144 | 48 | 1.02 (0.71, 1.47) | 0.923 | 0.98 (0.68, 1.43) | 0.932 |
TT | 95 | 31.7 | 86 | 28.7 | 1.00 | 1.00 | ||
rs10915437 | ||||||||
GG | 32 | 10.7 | 37 | 12.3 | 0.97 (0.57, 1.65) | 0.919 | 0.98 (0.58, 1.67) | 0.948 |
AG | 140 | 46.7 | 119 | 39.7 | 1.32 (0.94, 1.86) | 0.107 | 1.35 (0.96, 1.91) | 0.086 |
AA | 128 | 42.7 | 144 | 48 | 1.00 | 1.00 | ||
rs12134493b | ||||||||
AA or AC | 26 | 8.6 | 39 | 13 | 0.64 (0.38, 1.07) | 0.090 | 0.64 (0.38, 1.08) | 0.092 |
CC | 274 | 91.3 | 261 | 87 | 1.00 | 1.00 | ||
rs13208321c | ||||||||
AA or AG | 16 | 5.3 | 29 | 9.7 | 0.53 (0.28, 0.99) | 0.047 | 0.51 (0.27, 0.97) | 0.039 |
GG | 284 | 94.7 | 271 | 90.3 | 1.00 | 1.00 | ||