| TN and psychiatric illness | Control cohort | P values | |
---|---|---|---|---|
No. | 3273 | 13,092 | Â | |
Age (years)a | 45.6 (33.9–54.8) | 45.6 (33.9–54.8) | 0.999 | |
Distribution of age | Â | Â | Â | |
 | 20–39 | 1299 (39.7) | 5196 (39.7) | 0.999 |
 | 40–59 | 1423 (43.5) | 5692 (43.5) | 0.999 |
 | ≥60 | 551 (16.8) | 2204 (16.8) | 0.999 |
Sex | Â | Â | Â | |
 | Female | 1255 (38.3) | 5020 (38.3) | 0.999 |
 | Male | 2018 (61.7) | 8072 (61.7) |  |
Comorbidities | Â | Â | Â | |
 | Hypertension | 725 (22.2) | 2192 (16.7) | <0.001* |
 | Diabetes mellitus | 442 (13.5) | 1285 (9.8) | <0.001* |
 | Dyslipidemia | 717 (21.9) | 1795 (13.7) | <0.001* |
 | Coronary artery disease | 25 (0.8) | 91 (0.7) | 0.650 |
 | Congestive heart failure | 71 (2.2) | 226 (1.7) | 0.090 |
 | Cerebrovascular disease | 134 (4.1) | 421 (3.2) | 0.014 |
 | Chronic pulmonary disease | 591 (18.1) | 1318 (10.1) | <0.001* |
 | Malignancy | 48 (1.5) | 213 (1.6) | 0.581 |
Income | Â | Â | <0.001* | |
 | Low income | 1199 (36.6) | 5732 (43.8) |  |
 | Medium income | 1315 (40.2) | 4982 (38.1) |  |
 | High income | 759 (23.2) | 2378 (18.2) |  |
Degree of urbanization | Â | Â | 0.072 | |
 | Urban | 2112 (64.5) | 8172 (62.4) |  |
 | Suburban | 938 (28.7) | 3940 (30.1) |  |
 | Rural | 223 (6.8) | 980 (7.5) |  |
Follow-up, yearsa | 3.08 (1.92–3.98) | 3.08 (1.92–3.99) | 0.852 | |
Newly diagnosed psychiatric disorders, N (%) | Â | Â | Â | |
 | Schizophrenia | 3 (0.09) | 5 (0.04) | 1.000 |
 | Bipolar disorder | 1 (0.09) | 6 (0.05) | 0.203 |
 | Depressive disorder | 73 (2.23) | 103 (0.79) | <0.001* |
 | Anxiety disorder | 59 (1.80) | 79 (0.60) | <0.001* |
 | Sleep disorder | 40 (1.22) | 74 (0.57) | <0.001* |