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Table 3 Reduction of maximal pain per migraine day

From: Improvement of migraine symptoms with a proprietary supplement containing riboflavin, magnesium and Q10: a randomized, placebo-controlled, double-blind, multicenter trial

Intensity (SD) Verum Placebo P value
  N = 55 N = 57  
Baseline 2.71 (0.458) 2.70 (0.533) -
Treatment 1st month 2.55 (0.503) 2.63 (0.620) 0.17
Treatment 2nd month 2.44 (0.572) 2.53 (0.630) 0.53
Treatment 3rd month 2.47 (0.639) 2.64 (0.520) 0.03
Patients (%) Verum Placebo P value
  N = 55 N = 57  
Baseline    -
- mild 0 (0) 2 (3.5)  
- moderate 16 (29.1) 13 (22.8)  
- severe 39 (70.9) 42 (73.7)  
Treatment 3rd month    0.03
- mild 4 (7.3) 1 (1.8)  
- moderate 20 (36.4) 18 (31.6)  
- severe 29 (52.7) 37 (64.9)