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Table 4 Adjusted odds ratios (logistic regression) and associated confidence intervals for headache impact measures comparing the two menstrual migraine groups to the menstrually-unrelated migraine group, adjusting for potential confounders in two separate models 1,2

From: Burden of migraine related to menses: results from the AMPP study

Outcome

Group 3

Headache-Days Frequency (per 3 months)

<=6

<=45

MODEL

MODEL

I 1

II 2

I 1

II 2

Odds Ratio for MIDAS LPT4 (0.5+ Days vs <0.5 Days)5

MM

2.4 (1.1-5.1) 7

2.0 (0.9-4.3)

2.1 (1.1-3.8) 7

1.9 (1.0-3.5) 7

MAM

1.3 (0.9-1.9)

1.2 (0.8-1.9)

1.5 (1.2-2.0) 6

1.5 (1.1-1.9) 6

Odds Ratio for MIDAS LPT4 (2+ Days vs <2 Days)5

MM

5.4 (1.8-15.7) 6

5.1 (1.7-15.3) 6

2.6 (1.2-5.5) 7

2.7 (1.2-5.7) 7

MAM

1.8 (0.9-3.7)

1.6 (0.8-3.4)

1.9 (1.3-2.9) 6

1.8 (1.2-2.6) 6

Odds ratio for HIT-6 sum score of 56+ vs <568

MM

2.5 (1.3-4.7) 7

1.7 (0.9-3.3)

2.0 (1.1-3.3) 7

1.9 (1.1-3.3) 7

MAM

1.4 (1.1-1.9) 6

1.3 (0.9-1.8)

1.5 (1.2-1.9) 6

1.4 (1.1-1.8) 6

Odds ratio for HIT-6 sum score of 60+ vs <609

MM

4.0 (2.1-7.3) 6

2.9 (1.5-5.5) 6

3.0 (1.8-4.9) 6

2.9 (1.7-5.1) 6

MAM

1.4 (1.0-1.9) 7

1.4 (0.9-1.9)

1.6 (1.3-2.0) 6

1.5 (1.2-2.0) 6

  1. 1-Includes age, race, education level, household income and age of migraine onset as covariates.
  2. 2- Includes the covariates from footnote “1” and headache attack frequency per month.
  3. 3- MM = self-reported predominanty menstrual migraine, MAM = self-reported menstrually-associated migraine, MUM = self-reported menstrually- unrelated migraine.
  4. 4-Lost Productive Time.
  5. 5-Restricted modeling: removed ‘other’ employed and MIDAS LPT models only includes those full time or part time employed.
  6. 6- Indicates migraine group significance using Type III test at P-value <0.01.
  7. 7-Indicates migraine group significance using Type III test at P-value <0.05.
  8. 8 – This cut-score divides individuals with some impact or less from those with substantial impact or more.
  9. 9 – This cut-score divides individuals with substantial impact or less from those with very severe impact or more.
  10. In bold, values of statistical significance.