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Table 3 Multivariable* adjusted hazard ratios (95% confidence intervals) of brain tumor stratified by age according to headache status in the Women’s Health Study (N = 39,534)

From: Headache, migraine and risk of brain tumors in women: prospective cohort study

  

No headache (n = 26,512)

 

Any headache (n = 13,022)

 

Non-migraine headache (n = 5,731)

 

Any migraine (n = 7,291)

 

No. of cases

Hazard ratio* (95% CI)

No. of cases

Hazard ratio* (95% CI)

No. of cases

Hazard ratio* (95% CI)

No. of cases

Hazard ratio* (95% CI)

<55 years of age at baseline (N = 23,849)

13

1.00 (ref)

12

1.57 (0.72, 3.46)

6

1.79 (0.68, 4.72)

6

1.40 (0.53, 3.69)

≥55 years of age at baseline (N = 15,685)

19

1.00 (ref)

8

1.10 (0.48, 2.53)

4

1.28 (0.43, 3.78)

4

0.96 (0.33, 2.85)

  1. *Adjusted for age, body mass index (BMI) (<25, 25–29.9, ≥30 kg/m2), alcohol consumption (rarely/never, 1–3 drinks/months, 1–6 drinks/week, ≥1 drink/day), smoking status (never, past, current), postmenopausal status (premenopausal, postmenopausal, uncertain), and exercise (rarely/never, <1 time/week, 1–3 times/week, ≥4 times/week).