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Table 2 Age- and multivariable* adjusted hazard ratios (95% confidence intervals) of brain tumor according to headache status in the Women’s Health Study (N = 39,534)

From: Headache, migraine and risk of brain tumors in women: prospective cohort study

  

No headache (n = 26,512)

 

Any headache (n = 13,022)

 

Non-migraine headache (n = 5,731)

 

Any migraine (n = 7,291)

 

No. of cases

Hazard ratio (95% CI)

No. of cases

Hazard ratio (95% CI)

No. of cases

Hazard ratio (95% CI)

No. of cases

Hazard ratio (95% CI)

Age-adjusted

32

1.00 (ref)

20

1.35 (0.77, 2.37)

10

1.53 (0.75, 3.13)

10

1.21 (0.59, 2.47)

Multivariable adjusted*

32

1.00 (ref)

20

1.33 (0.76, 2.34)

10

1.53 (0.75, 3.12)

10

1.18 (0.58, 2.41)

  1. *Adjusted for age, body mass index (BMI) (<25, 25–29.9, ≥30 kg/m2), alcohol consumption (rarely/never, 1–3 drinks/months, 1–6 drinks/week, ≥1 drink/day), smoking status (never, past, current), postmenopausal status (premenopausal, postmenopausal, uncertain), and exercise (rarely/never, <1 time/week, 1–3 times/week, ≥4 times/week).