The second to fourth digit ratio (2D:4D): a risk factor of migraine and Tension-type headache

Table 1 The study sample’s demographic data and 2D:4D ratios

Characteristic	Migraine	TTH	Non	p value
Number	279	300	312
Gender				0.118
Males	83 (29.7%)	102 (34%)	118 (37.8%)
Females	196 (70.3%)	198 (66%)	194 (62.2%)
Age	37.3 ± 9.5	37.0 ± 8.8	36.8 ± 11.6	0.167
Family history	79 (28.3%)	58 (19.3%)	6 (1.9%)	0.000
Total
Left 2D:4D	0.946 ± 0.034^*†	0.947 ± 0.035^*†	0.954 ± 0.040^†	0.013
Right 2D:4D	0.953 ± 0.035^*	0.954 ± 0.036^*	0.961 ± 0.038	0.012
Males
Left 2D:4D	0.944 ± 0.034	0.950 ± 0.036	0.953 ± 0.043	0.267
Right 2D:4D	0.953 ± 0.034	0.954 ± 0.037	0.954 ± 0.039^‡	0.990
Females
Left 2D:4D	0.947 ± 0.034^*	0.946 ± 0.034^*	0.955 ± 0.038	0.030
Right 2D:4D	0.952 ± 0.035^*	0.954 ± 0.035^*	0.965 ± 0.037	0.001

^*Significant difference for migraine versus Non、TTH versus Non on both hands in total and female subjects (p < 0.05).
^†Significant difference for right hand versus left hand in total subjects (p < 0.05).
^‡Significant difference for male versus female in right hand in control group (p < 0.05).

ISSN: 1129-2377