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Table 1 The study sample’s demographic data and 2D:4D ratios

From: The second to fourth digit ratio (2D:4D): a risk factor of migraine and Tension-type headache

Characteristic Migraine TTH Non p value
Number 279 300 312  
Gender     0.118
 Males 83 (29.7%) 102 (34%) 118 (37.8%)  
 Females 196 (70.3%) 198 (66%) 194 (62.2%)  
Age 37.3 ± 9.5 37.0 ± 8.8 36.8 ± 11.6 0.167
Family history 79 (28.3%) 58 (19.3%) 6 (1.9%) 0.000
Total     
 Left 2D:4D 0.946 ± 0.034*† 0.947 ± 0.035*† 0.954 ± 0.040 0.013
 Right 2D:4D 0.953 ± 0.035* 0.954 ± 0.036* 0.961 ± 0.038 0.012
Males     
 Left 2D:4D 0.944 ± 0.034 0.950 ± 0.036 0.953 ± 0.043 0.267
 Right 2D:4D 0.953 ± 0.034 0.954 ± 0.037 0.954 ± 0.039 0.990
Females     
 Left 2D:4D 0.947 ± 0.034* 0.946 ± 0.034* 0.955 ± 0.038 0.030
 Right 2D:4D 0.952 ± 0.035* 0.954 ± 0.035* 0.965 ± 0.037 0.001
  1. *Significant difference for migraine versus Non、TTH versus Non on both hands in total and female subjects (p < 0.05).
  2. Significant difference for right hand versus left hand in total subjects (p < 0.05).
  3. Significant difference for male versus female in right hand in control group (p < 0.05).