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Table 4 Relation between high sensitivity C-reactive protein and location of cerebral white matter hyperintensities, headache characteristics, and sex differences in migraine patients*

From: High sensitivity C-reactive protein and cerebral white matter hyperintensities on magnetic resonance imaging in migraine patients

Parameters

hs-CRP (mg/L)

P ≤†

Juxtacortical WMHs

Present

1.95 ± 2,22

1.13 (0.21 – 9.40)

NS

Absent

1.94 ± 2,01

1.25 (0.10 – 9.92)

Subcortical WMHs

Present

2.01 ± 2.20

1.35 (0.10 – 9.92)

NS

Absent

1.91 ± 1,95

1.18 (0.19 – 9.80)

Periventricular WMHs

Present

1.91 ± 0.83

2.04 (1.02 – 2.67)

NS

Absent

1.94 ± 2.04

1.24 (0.10 – 9.92)

Sex

Female

1.99 ± 2.14

1.21 (0.01 – 9.92)

NS

Male

1.80 ± 1.62

1.35 (0.10 – 8.30)

Migraine disease duration (y)

≤1

1.46 ± 2.04

0.75 (0.15 – 9.51)

NS

2-6

1.92 ± 1.87

1.35 (0.10 – 9.40)

≥7

2.10 ± 2.18

1.31 (0.10 – 9.92)

Headache duration (h)

r = -0.002

NS

Visual analog score

r = -0.028

NS

Headache frequency (no./mo)

r = 0.042

NS

  1. *Data reported as mean ± SD, number of subjects (%), median (range, minimum to maximum), or correlation coefficient r between hs-CRP and parameters. Abbreviations: hs-CRP high sensitivity C-reactive protein, WMH white matter hyperintensity.
  2. †NS, not significant (P > .05).