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Table 2 Mean, standard deviation (SD) and interquartile range (IQR) [25 th percentile; 75 th percentile] for the amplitude of contact heat evoked potentials of the volar forearm (2a) and the pooled cheek (right and left cheek, 2b) of migraine patients and healthy controls for trains without and with performing the calculation task for blocks 1 to 4 of train 1 and train 2

From: Contact heat evoked potentials and habituation measured interictally in migraineurs

a
Volar forearm without performing the calculation task
  Migraine patients Healthy controls
Amplitude (μV) Mean SD IQR Mean SD IQR
Ampl_1_1 56.33 22.38 [48.80; 77.50] 66.09 24.93 [51.38; 79.28]
Ampl_1_2 48.57 25.73 [31.00; 76.70] 56.21 24.58 [40.93; 75.82]
Ampl_1_3 43.78 22.73 [29.20; 58.10] 51.11 27.48 [41.10; 55.10]
Ampl_1_4 43.32 22.27 [29.60; 61.10] 47.39 22.92 [35.08; 66.35]
Ampl_2_1 47.55 20.33 [33.30; 98.50] 57.36 26.81 [47.20; 80.05]
Ampl_2_2 42.30 18.59 [28.36; 59.80] 48.51 24.06 [40.58; 59.03]
Ampl_2_3 43.15 20.76 [24.75; 63.30] 47.32 23.96 [34.20; 65.10]
Ampl_2_4 36.50 18.02 [25.20; 48.60] 49.05 23.59 [28.88; 58.75]
p value of train 1 (power) p = 0.006 (0.74) chi-square = 9.579; df = 2 p < 0.001 (0.94) chi-square = 20.667; df = 2
p value of train 2 (power) p = 0.001 (0.73) chi-square = 13.875; df = 2 p = 0.001 (0.32) chi-square = 14.632; df = 2
Volar forearm with performing the calculation task
  Migraine patients Healthy controls
Amplitude (μV) Mean SD IQR Mean SD IQR
Ampl_1_1 35.80 13.60 [32.20; 57.45] 39.96 29.61 [21.04; 60.38]
Ampl_1_2 34.75 15.33 [32.42; 59.58] 39.69 29.23 [21.37; 55.70]
Ampl_1_3 29.56 13.21 [21.52; 47.58] 34.43 24.98 [20.99; 55.75]
Ampl_1_4 30.30 11.85 [26.63; 48.80] 30.95 25.74 [16.93; 50.00]
Ampl_2_1 36.80 13.41 [32.99; 47.63] 44.87 35.63 [23.51; 52.35]
Ampl_2_2 32.15 12.41 [23.38; 44.78] 39.04 25.35 [23.27; 56.53]
Ampl_2_3 32.40 11.27 [26.82; 44.25] 31.29 27.05 [20.11; 45.88]
Ampl_2_4 29.78 8.98 [22.26; 38.48] 42.24 26.86 [18.72; 66.38]
p value of train 1 (power) p = 0.176 (0.49) chi-square = 4.000; df = 2 p = 0.018 (0.31) chi-square = 9.385; df = 2
p value of train 2 (power) p = 0.199 (0.80) chi-square = 4.500; df = 2 p = 0.662 (0.06) chi-square = 1.500 ; df = 2
b
Pooled cheek without performing the calculation task
  Migraine patients Healthy controls
Amplitude (μV) Mean SD IQR Mean SD IQR
Ampl_1_1 53.07 20.41 [38.44; 68.10] 55.91 24.72 [41.77; 69.05]
Ampl_1_2 44.85 17.99 [31.56; 54.63] 43.74 16.83 [32.04; 50.83]
Ampl_1_3 41.76 18.05 [29.98; 49.60] 44.82 18.82 [34.23; 54.35]
Ampl_1_4 39.15 22.90 [27.27; 49.00] 40.24 14.69 [29.85; 51.39]
Ampl_2_1 40.20 15.53 [27.89; 55.10] 44.00 18.43 [30.20; 59.70]
Ampl_2_2 35.38 12.89 [27.64; 44.45] 38.84 13.15 [27.30; 47.70]
Ampl_2_3 36.61 16.55 [24.59; 46.40] 36.80 11.86 [30.60; 40.70]
Ampl_2_4 34.10 14.50 [21.94; 44.77] 36.47 14.57 [25.51; 48.70]
p value of train 1 (power) p < 0.001 (0.99) chi-square = 24.057; df = 2 p = 0.001 (0.999) chi-square = 15.895; df = 2
p value of train 2 (power) p = 0.007 (0.75) chi-square = 9.235; df = 2 p = 0.038 (0.84) chi-square = 6.359; df = 2
Pooled cheek with performing the calculation task
  Migraine patients Healthy controls
Amplitude (μV) Mean SD IQR Mean SD IQR
Ampl_1_1 31.72 11.30 [25.40; 44.25] 36.16 21.46 [20.74; 53.10]
Ampl_1_2 28.53 9.90 [25.49; 38.85] 31.83 14.08 [21.04; 42.55]
Ampl_1_3 25.83 9.29 [20.68; 37.10] 30.08 12.77 [19.44; 44.19]
Ampl_1_4 26.71 6.26 [22.39; 32.25] 26.76 8.37 [19.95; 34.27]
Ampl_2_1 34.73 12.22 [24.20; 46.40] 32.07 18.22 [18.80; 49.00]
Ampl_2_2 31.42 9.38 [27.28; 38.30] 27.17 11.60 [19.51; 69.91]
Ampl_2_3 27.87 8.27 [20.30; 34.00] 26.75 11.90 [18.88; 37.80]
Ampl_2_4 25.45 10.05 [16.33; 32.10] 25.66 10.29 [19.92; 34.87]
p value of train 1 (power) p = 0.401 (0.96) chi-square = 3.000; df = 2 p = 0.010 (1.00) chi-square = 8.957; df = 2
p value of train 2 (power) p < 0.001 (0.999) chi-square = 16.300; df = 2 p = 0.287 (0.70) chi-square = 3.111; df = 2
  1. The p value and power for each train is presented for block 1 vs. block 4.
  2. Statistical comparison with Friedman test for multiple pairwise comparison (blocks 1, 2 and 4), p < 0.05 is considered to be significant.