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EHMTI-0292. The effect of body fat mass and fat free mass on migraine headache

Introduction

Obesity seems to be associated to migraine headache. Increase in body fat, especially ingluteofemoral region, elevates adiponectin and leptin secretion which in turn impair inflammatory processes that could be contributing to migraine risk.

Aims

This study was designed to assess the relationship between body composition and risk of migraine.

Methods

In this cross-sectional study, 1510 middle-aged women who were visited in a weight reduction clinic of university were recruited. Migraine was diagnosed with HIS criteria. Body composition parameters including total fat mass (FATM), total fat free mass (FFM), truncal fat mass (TFATM), and truncal fat free mass (TFFM) was assessed using bioelectric impedance. We further assessed cardiovascular risk factors and smoking as confounding factors. To determine the real association between different variables and risk of migraine, the associations were adjusted by multivariate logistic regression analysis.

Results

Elevation in fasting blood sugar, total cholesterol, LDL cholesterol, FFM, TFFM, and waist-to-hip ratio increased the risk of migraine. When the associations were adjusted for other factors, only the association between migraine and FFM remained statistically significant.

Conclusion

Lower FFM increased the risk of migraine in overweight and obese individuals. In the other words, higher fat free mass could be a protective factor for migraine.

No conflict of interest.

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Correspondence to S Razeghi jahromi.

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Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (https://creativecommons.org/licenses/by/4.0), which permits use, duplication, adaptation, distribution, and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.

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jahromi, S.R., Abolhasani, M., Meysamie, A. et al. EHMTI-0292. The effect of body fat mass and fat free mass on migraine headache. J Headache Pain 15, E29 (2014). https://doi.org/10.1186/1129-2377-15-S1-E29

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Keywords

  • Migraine
  • Body Composition
  • Migraine Headache
  • Bioelectric Impedance
  • Fast Blood Sugar