EHMTI-0228. A clinical interview versus prospective headache diaries in the diagnosis of menstrual migraine without aura

Introduction

The International Classification of Headache Disorders (ICHD) II and III beta defines menstrual migraine as attacks of migraine without aura occurring on day 1±2 of the menstrual cycle in ≥2/3 menstruations. According to the ICHD III beta, a three month prospective headache diary is required in order to establish the diagnosis of MM.

Aims

To compare the diagnosis of MM from a clinical interview based on the ICHD II-criteria for MM, with prospective headache diaries in a population-based study.

Methods

237 women with self-reported migraine in at least half of menstruations were interviewed by a neurologist about headache and diagnosed according to ICHD II. Additionally, the MM-criteria were expanded to include other types of migraine related to menstruation. Subsequently, all women were asked to complete three month prospective headache diaries.

Results

A total of 123 (52%) women completed both clinical interview and diaries. Thirty-eight women were excluded from the analyses; two had incomplete diaries and 36 women recorded £1 menstruation, leaving 85 diaries eligible for analysis. Sensitivity, specificity, positive and negative predictive value and Kappa for the diagnosis of MM in clinical interview vs. headache diary were 82%, 83%, 90%, 71% and 0.62 (95% CI 0.46-0.80). Using a broader definition of MM, Kappa was 0.64 (95% CI 0.47-0.83).

Conclusion

A thorough clinical interview is valid for the diagnosis of MM. When this is undertaken, prospective headache diaries should not be mandatory to diagnose MM but may be necessary to exclude a chance association.

No conflict of interest.