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EHMTI-0331. Q-No: a questionnaire to predict nocebo in outpatients seeking neurological consultation

Background and aim

Nocebo affects significantly adherence and treatment outcome and varies considerably among neurological conditions. We aimed to evaluate a questionnaire to predict nocebo in outpatients seeking neurological consultation.

Methods

A four-item (rating range 0-20) self-fulfilled questionnaire (Q-No) was given in outpatients seeking neurological consultation at the Athens Naval Hospital. A blind to Q-No scoring neurologist rated outpatients as nocebo or no-nocebo after follow-up of >6 months.

Results

338 (71.6% females) patients with mean age 46.9 (±13.8) years fulfilled the Q-No and the mean total score was 13.2 (±3.7). The Crombach's alpha coefficient was 0.627. Neurologist suggested 80 patients (23.7%) as nocebo and 258 as no-nocebo (mean Q-No score=12.4 95% CI: [12.0-12.9] and 15.8, 95%CI: [15.1-16.6], respectively). By using a cut-off at score 16 the Q-No predicts nocebo with 82.6% specificity and 61.3% sensitivity.

Conclusions

Q-No may serve as a useful tool to predict nocebo in outpatients seeking neurological consultation.

No conflict of interest.

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Correspondence to C Deligianni.

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Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (https://creativecommons.org/licenses/by/4.0), which permits use, duplication, adaptation, distribution, and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.

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Deligianni, C., Mitsikostas, D. EHMTI-0331. Q-No: a questionnaire to predict nocebo in outpatients seeking neurological consultation. J Headache Pain 15, D14 (2014). https://doi.org/10.1186/1129-2377-15-S1-D14

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  • DOI: https://doi.org/10.1186/1129-2377-15-S1-D14

Keywords

  • Public Health
  • Internal Medicine
  • Treatment Outcome
  • Alpha Coefficient
  • Neurological Condition