Table 3 The severities of pain indices and depression at baseline and post-4-week treatment between groups in 85 patients with major depressive disorder ^a

HAMD scores

24.2 ± 3.9

22.2 ± 3.5*

24.1 ± 4.1

22.3 ± 3.5*

14.8 ± 6.6

10.6 ± 5.8**

13.4 ± 7.0

12.1 ± 6.0

Bone and/or joints

Intensity

3.7 ± 3.2

1.3 ± 3.1**

3.1 ± 3.3

1.9 ± 2.5

2.1 ± 3.1

0.5 ± 1.0**

1.6 ± 2.7

1.0 ± 2.2

Frequency

3.1 ± 2.9

1.2 ± 2.1**

2.7 ± 3.0

1.6 ± 2.2

1.7 ± 2.4

0.7 ± 1.7*

1.6 ± 2.4

0.8 ± 1.8

Head

Intensity

6.4 ± 2.6

2.4 ± 2.5**

5.1 ± 3.0

3.8 ± 2.4

4.0 ± 3.2

2.0 ± 2.5**

3.1 ± 3.2

2.9 ± 3.0

Frequency

4.7 ± 2.4

1.8 ± 2.1**

3.7 ± 2.6

2.8 ± 2.8

3.2 ± 2.4

1.1 ± 1.4**

2.8 ± 2.5

1.6 ± 1.8*

Back

Intensity

4.3 ± 3.0

1.6 ± 2.3**

3.6 ± 3.3

2.5 ± 2.6

2.1 ± 2.7

0.7 ± 1.4**

1.6 ± 2.3

1.2 ± 2.2

Frequency

3.9 ± 2.8

1.9 ± 2.5**

3.1 ± 2.9

2.7 ± 2.8

2.1 ± 2.4

0.9 ± 2.0*

1.8 ± 2.3

1.2 ± 2.2

Abdomen

Intensity

2.7 ± 2.7

1.2 ± 1.9**

2.2 ± 2.7

1.7 ± 2.2

1.6 ± 2.2

0.5 ± 1.1**

1.3 ± 2.2

0.8 ± 1.4

Frequency

2.6 ± 2.5

1.0 ± 1.7**

2.3 ± 2.6

1.4 ± 1.9

1.5 ± 2.1

0.5 ± 1.3**

1.5 ± 2.3

0.6 ± 0.9*

Chest

Intensity

3.1 ± 3.4

2.0 ± 2.9

2.7 ± 3.3

2.4 ± 3.2

1.8 ± 2.8

0.3 ± 0.8**

1.2 ± 2.4

0.9 ± 2.1

Frequency

2.3 ± 2.5

1.5 ± 2.4

1.8 ± 2.3

2.0 ± 2.7

1.1 ± 1.7

0.2 ± 0.6**

0.7 ± 1.4

0.7 ± 1.3

Neck and/or shoulder

Intensity

6.9 ± 2.6

3.7 ± 3.2**

5.9 ± 3.5

4.8 ± 3.0

4.1 ± 3.4

1.6 ± 2.1**

3.4 ± 3.3

2.4 ± 2.8

Frequency

5.9 ± 2.0

3.8 ± 3.0**

5.1 ± 2.8

4.7 ± 2.7

4.2 ± 2.4

2.4 ± 2.9**

4.0 ± 2.7

2.7 ± 2.8*

General muscle

Intensity

4.4 ± 3.1

1.9 ± 2.6**

3.4 ± 3.0

3.0 ± 3.3

2.5 ± 3.3

0.8 ± 1.7**

1.9 ± 2.9

1.5 ± 2.6

Frequency

4.0 ± 3.0

2.1 ± 2.6**

3.5 ± 3.1

2.5 ± 2.7

2.3 ± 2.9

1.0 ± 2.2*

2.0 ± 2.9

1.3 ± 2.4

Limbs

Intensity

2.1 ± 2.5

0.8 ± 1.8**

1.7 ± 2.5

1.2 ± 2.2

1.1 ± 2.0

0.3 ± 1.0*

0.9 ± 1.7

0.5 ± 1.5

Frequency

1.9 ± 2.5

0.8 ± 1.9*

1.8 ± 2.6

1.0 ± 1.8

1.0 ± 1.7

0.4 ± 1.2*

0.9 ± 1.6

0.5 ± 1.4