Table 5 Factors associated with retention refill of index triptan at 2 years
From: Treatment adherence among new triptan users: a 2-year cohort study in Taiwan
Univariate | Multivariate | |||
|---|---|---|---|---|
Variable | Odds ratio (95 CI) | p value | Odds ratio (95 CI) | p value |
Age | ||||
20-40 | 1 | |||
≥40 | 1.06 (0.89-1.26) | 0.509 | ||
Male | 1.15 (0.94-1.39) | 0.170 | ||
Urbanization | ||||
Level 1 (Most urbanized) | 1 | |||
Level 2 | 0.93 (0.78-1.11) | 0.425 | ||
Level 3 | 0.63 (0.39-1.02) | 0.061 | ||
Level 4 (Least urbanized) | 1.05 (0.43-2.60) | 0.909 | ||
Monthly income (NT$) | ||||
Dependent | 1 | |||
NT$ 0–19,200 | 0.80 (0.61-1.07) | 0.131 | ||
NT$ 19,200-42,000 | 1.22 (0.96-1.56) | 0.108 | ||
>NT$ 42,000 | 2.12 (1.62-2.77) | <0.001 | ||
Diabetes mellitus | 0.47 (0.32-0.71) | <0.001 | 0.59 (0.39-0.89) | 0.011 |
Cerebrovascular diseases | 0.74 (0.52-1.04) | 0.085 | ||
Peripheral vascular disease | 0.87 (0.41-1.86) | 0.721 | ||
Frequency of ambulatory visit for headache within one year before index date | 0.99 (0.99-1.01) | 0.892 | ||
Neurologic ambulatory visit for headache within one year before index date | 1.04 (1.02-1.07) | 0.001 | 1.05 (1.02-1.07) | 0.002 |
First prescription including triptans and other acute medications | 1.07 (0.90-1.27) | 0.427 | ||
First prescription of triptan by neurologists | 3.02 (2.37-3.84) | <0.001 | 2.70 (2.12-3.45) | <0.001 |
Use of at least one prophylactic agent* | 1.03 (0.86-1.24) | 0.722 | ||
Hospital level of first prescription of triptan | ||||
Level I (Medical center) | 1 | 1 | ||
Level II | 0.71 (0.58-0.86) | 0.001 | 0.74 (0.60-0.90) | 0.003 |
Level III | 0.86 (0.68-1.11) | 0.247 | 0.91 (0.71-1.17) | 0.476 |
Level IV (Local medical clinics) | 0.36 (0.22-0.61) | <0.001 | 0.34 (0.20-0.58) | <0.001 |