Table 4 Factors associated with continuing using index triptan at first refill
From: Treatment adherence among new triptan users: a 2-year cohort study in Taiwan
Univariate | Multivariate | |||
|---|---|---|---|---|
Variable | Odds ratio (95 CI) | p value | Odds ratio (95 CI) | p value |
Age | ||||
20-40 | 1 | |||
≥40 | 0.88 (0.82-0.94) | <0.001 | ||
Male | 0.97 (0.89-1.05) | 0.461 | ||
Urbanization | ||||
Level 1 (Most urbanized) | 1 | |||
Level 2 | 0.91 (0.85-0.98) | 0.012 | ||
Level 3 | 0.77 (0.65-0.92) | 0.003 | ||
Level 4 (Least urbanized) | 0.70 (0.47-1.06) | 0.096 | ||
Monthly income (NT$) | ||||
Dependent | 1 | |||
NT$ 0–19,200 | 1.05 (0.94-1.16) | 0.377 | ||
NT$ 19,200-42,000 | 1.16 (1.05-1.28) | 0.003 | ||
>NT$ 42,000 | 1.46 (1.29-1.64) | <0.001 | ||
Diabetes mellitus | 0.62 (0.54-0.71) | <0.001 | 0.75 (0.65-0.87) | <0.001 |
Cerebrovascular diseases | 0.77 (0.68-0.88) | <0.001 | ||
Peripheral vascular disease | 0.79 (0.58-1.08) | 0.136 | ||
Frequency of ambulatory visit for headache within one year before index date | 1.02 (1.02-1.03) | <0.001 | 1.01 (1.00-1.02) | 0.012 |
Neurologic ambulatory visit for headache within one year before index date | 1.09 (1.08-1.11) | <0.001 | 1.05 (1.04-1.07) | <0.001 |
First prescription including triptan and other acute medications | 1.35 (1.26-1.45) | <0.001 | 1.09 (1.01-1.17) | <0.001 |
First prescription of triptan by neurologists | 3.45 (3.17-3.77) | <0.001 | 3.08 (2.81-3.37) | <0.001 |
Use of at least one prophylactic agent* | 1.46 (1.35-1.58) | <0.001 | 1.37 (1.27-1.49) | <0.001 |
Hospital level of first prescription of triptan | ||||
Level I (Medical center) | 1 | 1 | ||
Level II | 0.95 (0.87-1.03) | 0.205 | 0.97(0.89-1.06) | 0.494 |
Level III | 0.98 (0.88-1.09) | 0.719 | 1.02 (0.91-1.14) | 0.717 |
Level IV (Local medical clinics) | 0.79 (0.68-0.92) | 0.002 | 0.74 (0.63-0.87) | <0.001 |