Table 3 Association between the 5-HTTLPR genotypes and triptan response in CH
From: Bi-allelic and tri-allelic 5-HTTLPR polymorphisms and triptan non-response in cluster headache
5-HTTLPR genotype | Crude model | Multivariable-adjusted model† | ||||
|---|---|---|---|---|---|---|
Bi-allelic | OR (95% CI) | p-value | p trend | OR (95% CI) | p-value | p trend |
LL | Referent | ---- | 0.98 | Referent | ---- | 0.98 |
LS | 0.72 (0.32-1.63) | 0.32 | 0.75 (0.32-1.73) | 0.40 | ||
SS | 1.06 (0.41-2.70) | 0.60 | 1.04 (0.40-2.72) | 0.66 | ||
Functional tri-allelic | ||||||
L*L* | Referent | ---- | 0.50 | Referent | 0.46 | |
L*S* | 1.24 (0.51-3.00) | 0.90 | 1.33 (0.53-3.32) | 0.79 | ||
S*S* | 1.40 (0.53-3.70) | 0.56 | 1.46 (0.54-3.98) | 0.56 | ||