Table 1 Baseline characteristics of triptan users overall and according to 5-HTTLPR polymorphism
From: Bi-allelic and tri-allelic 5-HTTLPR polymorphisms and triptan non-response in cluster headache
All triptan users (n = 148) | Bi-allelic 5-HTTLPR polymorphism | p-value† | Functional tri-allelic 5-HTTLPR polymorphism | p-value† | |||||
|---|---|---|---|---|---|---|---|---|---|
LL (n = 44) | LS (n = 70) | SS (n = 34) | L*L* (n = 37) | L*S* (n = 70) | S*S* (n = 41) | ||||
Age (mean ± SD), years | 44.6 ± 10.5 | 45.5 ± 12.0 | 43.9 ± 9.7 | 44.9 ± 10.3 | 0.82 | 45.5 ± 12.0 | 44.5 ± 10.1 | 44.0 ± 10.0 | 0.82 |
Men (%) | 115 (77.7) | 35 (79.6) | 53 (75.7) | 27 (79.4) | 0.86 | 29 (78.4) | 55 (78.6) | 31 (75.6) | 0.93 |
CH form,% | |||||||||
Episodic | 103 (69.6) | 27 (61.4) | 52 (74.3) | 24 (70.6) | 0.47 | 22 (59.5) | 50 (71.4) | 31 (75.6) | 0.28 |
Chronic | 28 (18.9) | 10 (22.7) | 13 (18.6) | 5 (14.7) | 8 (21.6) | 15 (21.4) | 5 (12.2) | ||
Undetermined periodicity | 17 (11.5) | 7 (15.9) | 5 (7.1) | 5 (14.7) | 7 (18.9) | 5 (7.1) | 5 (12.2) | ||