Figure 3

Acute prophylactic BBG treatment alleviates NTG-induced thermal hypersensitivity in wild-type mice. Mice were treated with 50 mg/kg BBG i.p. or an identical volume of saline 30 min before NTG treatment. PWT is expressed in % of baseline. Asterisks indicate statistical significant difference in respective PWT values from the saline-treated animals (n = 11-12 mice/group; Student’s t-test, **P < 0.01).