Table 2 Comparison of heart rate variability profiles between patients with RCVS in ictal and remission stages and controls

Time domain variables

SDNN, ms

129.4 ± 34.7

109.9 ± 24.8

0.006

120.7 ± 24.9

0.207

0.041

RMSSD, ms

35.2 ± 14.2

22.1 ± 7.0

<0.001

26.7 ± 11.1

0.005

0.019

pNN 50,%

10.6 ± 8.1

3.7 ± 3.4

<0.001

5.6 ± 6.3

0.003

0.070

Frequency domain variables

Total power, ln (ms²/Hz)

9.01 ± 0.50

8.47 ± 0.48

<0.001

8.71 ± 0.40

0.005

0.008

VLF (0.003 – 0.04 Hz), ln (ms²/Hz)

8.66 ± 0.48

8.21 ± 0.46

<0.001

8.43 ± 0.37

0.017

0.011

LF (0.04 – 0.15 Hz), ln (ms²/Hz)

7.32 ± 0.60

6.63 ± 0.62

<0.001

6.90 ± 0.53

0.001

0.020

HF (0.15 – 0.4 Hz), ln (ms²/Hz)

6.77 ± 0.74

5.82 ± 0.73

<0.001

6.21 ± 0.75

0.001

0.016

LF/HF, ratio

2.48 ± 1.07

3.38 ± 1.32

0.001

2.97 ± 1.25

0.067

0.013