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Table 4 Partial age-adjusted correlations1 between sleep, symptoms, pain thresholds, among interictal migraineurs subgroups

From: Sleep-related and non-sleep-related migraine: interictal sleep quality, arousals and pain thresholds

 

Sleep quality

Pain thresholds

Headache

NSM (n = 18)

Insomnia 2

PSQI 3

PPT

HPT

CPT

Headache days 4

Headache intensity (1–4)

Headache duration (years) 1

Sleep N1

0.12

0.41

0.16

0.02

0.16

0.60*

0.21

0.35

Sleep N2

0.18

0.26

0.29

-0.05

-0.04

0.18

0.08

-0.11

Sleep N3

-0.40

-0.47(*)

-0.50*

-0.18

-0.21

-0.24

0.03

-0.23

REM sleep

-0.15

-0.25

-0.04

0.08

-0.27

0.21

0.19

0.03

Fast arousal index

0.46(*)

0.45(*)

0.30

-0.19

-0.23

-0.34

-0.10

0.09

Slow arousal (KD-) index

0.13

-0.33

0.05

-0.57*

-0.57*

-0.64**

-0.01

-0.46(*)

SM (n = 15 5 )

Insomnia 2

PSQI 3

PPT

HPT

CPT

Headache days 4

Headache intensity (1–4)

duration (years)

Sleep N1

0.32

0.28

0.07

-0.12

0.08

0.11

0.19

-0.13

Sleep N2

-0.69**

-0.46(*)

0.54*

-0.20

0.08

-0.50(*)

0.04

0.28

Sleep N3

0.41

0.33

-0.36

-0.11

-0.44

0.39

-0.22

-0.63*

REM sleep

-0.13

-0.11

0.15

0.10

0.34

-0.40

-0.01

-0.06

Fast arousal index

0.30

0.26

0.15

-0.21

-0.08

-0.02

0.18

-0.53(*)

Slow arousal (KD-) index

-0.36

-0.01

0.53(*)

-0.19

-0.31

0.05

0.40

-0.12

  1. NSM: Non-sleep related migraine. SM: sleep related migraine.
  2. 1All variables were square root transformed before correlation was computed. SM: Sleep-related migraine attack subgroup and NSM: non-sleep-related migraine recorded in an interictal phase. PPT: pressure pain threshold, HPT: Heat pain threshold, CPT: cold pain threshold.
  3. 2Sum of four insomnia-questions in KSQ (Karolinska sleep questionnaire).
  4. 3Pittsburgh sleep quality index frequency of pain-related sleep problems during the last month from the PSQI questionnaire.
  5. 4Headache days last three months.
  6. 5One SM excluded from fast and slow arousal scoring because of loosened electrode.
  7. p < 0.10(*), p < 0.05*, p < 0.01** Significant differences are emphasized with bold types.