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Table 3 Quantitative analysis of total protein spots detected by 2-DE and total protein peaks detected by SELDI-TOF analysis

From: Discovery by a proteomic approach of possible early biomarkers of drug-induced nephrotoxicity in medication-overuse headache

Groups

N o. of spots (2-DE)

Increasevs controls (%)

N o. of peaks (SELDI-TOF)

Increasevs controls (%)

Controls

357 ± 22

N/A

34 ± 2.9

N/A

NSAIDs

536 ± 14**

50

53 ± 3.3*

56

Triptans

403 ± 29

13

40 ± 4.1

18

Mixtures

502 ± 18**

41

50 ± 2.6*

47

  1. Spots and peaks numbers are expressed as means ± SD. Statistical significance was tested using unpaired Student’s t-test (**p<0.001; *p<0.01 vs controls).
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The Journal of Headache and Pain

ISSN: 1129-2377

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