From: Genetic variants in the NOTCH4 gene influence the clinical features of migraine
 | Migraine patients | ||
---|---|---|---|
 | Total | Female | Male |
Total | 239 | 165 | 74 |
Age (mean ± SD) | 40.6 ± 13.0 | 40.7 ± 13.4 | 40.1 ± 11.9 |
Age at onset (mean ± SD) | 18.1 ± 9.9 | 18.22 ± 10.1 | 17.8 ± 9.7 |
Duration of disease (yrs ± SD) | 22.5 ± 13.5 | 22.6 ± 13.5 | 22.2 ± 13.6 |
Attacks/year | 56.2 ± 57.9 | 52.9 ± 53.9 | 63.6 ± 65.8 |
Migraine without aura | 190 | 130 | 60 |
Migraine with aura | 49 | 30 | 19 |
Positive Familial History | 184 | 137 | 47 |
Photophobia | 192 | 137 | 55 |
Phonophobia | 173 | 122 | 51 |
Nausea | 184 | 134 | 50 |
Vomiting | 121 | 91 | 30 |
Menstrual migraine | 116 | 116 | 0 |
STAI-x1 | 40.4 ± 11.4 | 41.5 ± 11.6 | 37.9 ± 10.6 |
STAI-x 2 | 44.2 ± 11.1 | 44.7 ± 11.2 | 43.2 ± 10.8 |
BDI | 9.9 ± 7.9 | 10.4 ± 8.0 | 8.8 ± 7.6 |