Figure 3

The vertical bar chart shows the frequency of side effects reports by > 30% of the subjects over 5 days of monosodium glutamate (MSG) (black) and 5 days of placebo (white) intervention. For most side effects, such as nausea and fatigue, there was a peak in reports on the second or third day of administration followed by a gradual decline in reports. There were substantially fewer reports of side effects in the placebo group, with the exception of reports of jaw soreness, which peaked during the first session and then declined. The Occurrence of headache and other side effects showed a significant difference between the interventions by McNemar’s test (*: P < 0.05).