Comparison of tolerability and efficacy of a combination of paracetamol + caffeine and sumatriptan in the treatment of migraine attack: a randomized, double-blind, double-dummy, cross-over study

Table 2 Sum of pain intensity differences (SPID) and total pain relief (TOTPAR) in the 4-h observation period for the ITT dataset (n = 264)

	PCF	SUM	All	t test
SPID
Baseline intensity	2.1 ± 0.7	2.1 ± 0.8	2.1 ± 0.8
Mean ± SD	3.2 ± 3.8	3.2 ± 3.7	3.2 ± 3.8	p = 0.88
TOTPAR
Mean ± SD	7.0 ± 3.6	7.4 ± 3.6	7.2 ± 3.6	p = 0.48

SD standard deviation
ANOVA for SPID and TOTPAR showed a positive independent significant variable for intensity of headache at baseline (p < 0.001), while no difference between type of treatment (p = 0.8849)

ISSN: 1129-2377