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Table 21 Preventive non-pharmacological treatments for cluster headache

From: Italian guidelines for primary headaches: 2012 revised version

Treatment

Level of evidence

Scientific strength of evidence

Clinical effectiveness

Adverse events

Level of recommendation

References

Anesthetic blockade

?

Rare

IV

[461]

Lesion of trigeminal nucleus

C

+

?

Rare, severe

IV

[462467]

Occipital nerve stimulation

C

?

Rare

IV

[468, 469]

Hypotalamic deep brain stimulation

B

++

+++

Rare, very severe

II (only for chronic refractory CH)

[423, 470, 471]