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Table 3 Optical densities of differentially expressed proteins in control subjects and MOH patients

From: Proteomic analysis of urine in medication-overuse headache patients: possible relation with renal damages

 

Control group

Triptans group

NSAIDs group

Mixtures group

UROM

2,205 ± 291

14,800 ± 2,764

12,500 ± 1,652

11,100 ± 982

AMBP

ND

ND

9,650 ± 1,393

ND

ZAZG

ND

ND

6,580 ± 969

ND

ITIH4

ND

ND

5,760 ± 941

7,560 ± 746

IGKC

ND

ND

6,200 ± 876

5,480 ± 1,216

RNAS2

ND

1,230 ± 231

1,450 ± 181

ND

CYTM

ND

1,125 ± 192

ND

ND

CYTC

ND

ND

1,340 ± 198

ND

  1. Optical densities, detected by “Quantity One” 1-D image analysis software (Bio-Rad), were expressed as means ± standard deviation. Seven proteins were over-secreted in NSAIDs group: OR = 49, 95% CI 2.53–948.67; RR = 7, 95% CI 1.09–44.60 vs. controls; OR = 11.6, 95% CI 0.92–147.57; RR = 5, 95% CI 0.74–33.77 vs. triptans and mixtures groups. Three proteins were over-secreted in triptans and mixtures groups: OR = 4.2, 95% CI 0.33–53.12; RR = 1.4, 95% CI 0.77–2.54 vs. controls
  2. ND protein not-detectable in the sample
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The Journal of Headache and Pain

ISSN: 1129-2377

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