Polymorphisms of the SCN1A gene in children and adolescents with primary headache and idiopathic or cryptogenic epilepsy: is there a linkage?

Table 1 Description of the polymorphisms of the SCN1A gene in this study

Base pair change	Aminoacid	Position	Frequency of heterozygous reported in literature	Clinical association	Reference
c.1748A > T	p.D583 V	Exon 11	ND	NK	NCBI
c.2656T > C	p.S886P	Exon 15	ND	NK	NCBI
c.3199A > G	p.T1067A	Exon 16	0.33	The SNP is more frequent in patients with epilepsy than in controls (33)	[24, 25, 27–33]
c.5771G > A	p.R1924H	Exon 26	ND	NK	NCBI
c.5864T > C	p.I1955T	Exon 26	0.025	NK	[41]

ISSN: 1129-2377