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Table 2 Neuropsychological tests results

From: Orbitofrontal dysfunction predicts poor prognosis in chronic migraine with medication overuse

 

Chronic migraine with drug overuse (n = 42)

Episodic migraine (n = 42)

Controls (n = 41)

p

Orbitofrontal tasks

 Faux-Pas

  Faux-Pas Composite Score

40 (0–59)

47 (0–60)

42 (25–59)

0.0397

  Detected Faux-Pas

8 (0–10)

9 (0–10)

8 (5–10)

0.0349

  Control questions

40 (38–40)

39.5 (37–40)

40 (37–40)

0.2115

  Intentionalitya

6 (0–10)

7 (0–10)

7 (3–10)

0.0034

  Empathyb

7 (0–10)

8 (0–10)

8 (4–10)

0.0825

 Reading the Mind in the Eyes

25 (18–31)

26 (14–32)

27 (16–35)

0.2035

 Empathy quotient

47 (20–65)

42 (28–59)

47.5 (21–70)

0.2970

Dorsolateral tasks

 Trail Making B

74 (37–210)

68 (30–203)

64 (30–119)

0.1306

 Letters and Numbers

10 (4–19)

10.5 (4–20)

13 (6–21)

0.0046

WCST

 Categories acquired

3 (0–5)

4 (1–5)

4 (0–6)

0.1020

 Perseverative errors

7 (2–21)

6 (3–29)

5 (0–22)

0.1116

 First category

12 (10–65)

11 (10–33)

12 (10–65)

0.0074

  1. Values expressed as median (range)
  2. WCST Wisconsin card sorting test
  3. aSubjects answered the question: Why do you think someone did the Faux-Pas? The patient gives an incorrect answer when he/she detects intention in the Faux-Pas (which was designed as unintentional); the lower the score, the worse performance
  4. bSubjects answered the question: How do you think the person affected by the Faux-Pas feels?