From: Orbitofrontal dysfunction predicts poor prognosis in chronic migraine with medication overuse
Chronic migraine with drug overuse (n = 42) | Episodic migraine (n = 42) | Controls (n = 41) | p | |
---|---|---|---|---|
Orbitofrontal tasks | ||||
Faux-Pas | ||||
Faux-Pas Composite Score | 40 (0–59) | 47 (0–60) | 42 (25–59) | 0.0397 |
Detected Faux-Pas | 8 (0–10) | 9 (0–10) | 8 (5–10) | 0.0349 |
Control questions | 40 (38–40) | 39.5 (37–40) | 40 (37–40) | 0.2115 |
Intentionalitya | 6 (0–10) | 7 (0–10) | 7 (3–10) | 0.0034 |
Empathyb | 7 (0–10) | 8 (0–10) | 8 (4–10) | 0.0825 |
Reading the Mind in the Eyes | 25 (18–31) | 26 (14–32) | 27 (16–35) | 0.2035 |
Empathy quotient | 47 (20–65) | 42 (28–59) | 47.5 (21–70) | 0.2970 |
Dorsolateral tasks | ||||
Trail Making B | 74 (37–210) | 68 (30–203) | 64 (30–119) | 0.1306 |
Letters and Numbers | 10 (4–19) | 10.5 (4–20) | 13 (6–21) | 0.0046 |
WCST | ||||
Categories acquired | 3 (0–5) | 4 (1–5) | 4 (0–6) | 0.1020 |
Perseverative errors | 7 (2–21) | 6 (3–29) | 5 (0–22) | 0.1116 |
First category | 12 (10–65) | 11 (10–33) | 12 (10–65) | 0.0074 |