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Table 1 Demographics and migraine information for patients and controls

From: Orbitofrontal dysfunction predicts poor prognosis in chronic migraine with medication overuse

 

Chronic migraine with drug overuse

Episodic migraine

Controls

N (females)

42 (39)

42 (35)

41 (30)

Age, mean (SD), years

41.21 (8.20)

36.19 (8.66)

37.12 (8.59)

Years of education

<12 years (17)

<12 years (16)

<12 years (9)

12–16 years (16)

12–16 years (14)

12–16 years (17)

>16 years (9)

>16 years (12)

>16 years (15)

Years with migraine

<5 years (5)

<5 years (9)

5–15 years (13)

5–15 years (15)

>15 years (24)

>15 years (18)

Medication overuse

NSAIDs (21), triptans (3), simple analgesics (4), combination of the above (14)

Preventive medication

Combinationa (15), amitriptyline (4), topiramate (4), zonisamide (1), beta-blockers (3), lamotrigine (1), flunaricine (1), SSRI (2), no treatment (11)

No treatment (26), beta-blockers (7), amitriptyline (7), flunaricine (2)

Follow-up at 1 year

Overuse persisted (24)

Continued without overuse (35)

Ceased overuse (16)

Started overuse (3)

Lost to follow-up (2)

Lost to follow-up (4)

  1. NSAIDs Non-steroidal anti-inflammatory drugs, SSRI selective serotonin reuptake inhibitors
  2. aMore than one drug (valproic acid, zonisamide, topiramate, beta-blockers)