Table 2 Genotypic, allelic, and haplotypic comparisons in HCRTR1 gene I408V polymorphism between migraine patients and controls
From: Evidence for an association between migraine and the hypocretin receptor 1 gene
HCRTR1 SNP3 I408V (rs2271933) | Chi | p | OR | 95% CI |
|---|---|---|---|---|
Alleles | ||||
A vs. G | χ2 = 8.108 | p = 0.004 | 1.42 | 1.11 < OR < 1.81 |
Genotypes | ||||
AA vs. GG | χ2 = 4.355 | p = 0.037 | 1.81 | 1.03 < OR < 3.19 |
GA vs. GG | χ2 = 7.556 | p = 0.006 | 1.42 | 1.11 < OR < 1.81 |
AA vs. GA | χ2 = 0.071 | p = 0.789 | 1.11 | 0.64 < OR < 1.95 |
GA+AA vs. GG (dominant model) | χ2 = 9.217 | p = 0.002 | 1.66 | 1.19 < OR < 2.32 |
AA vs. GG + GA (recessive model) | χ2 = 1.467 | p = 0.226 | 1.40 | 0.83 < OR < 2.30 |
Haplotypes | ||||
TTA | χ2 = 6.151 | p = 0.013 | 1.37 | 1.07 < OR < 1.74 |
TTG | χ2 = 25.537 | p = < 0.001 | 0.10 | 0.03 < OR < 0.30 |