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Table 2 Incidence, most common AEs, chest-related AEs in placebo-controlled RCTs after oral administration of zolmitriptan 2.5 mg [15, 33]

From: Optimal balance of efficacy and tolerability of oral triptans and telcagepant: a review and a clinical comment

 

Placebo (n = 401) (%)

Zolmitriptan 2.5 mg (n = 498) (%)

Patients with at least one AE

117 (29)

227 (46)

Most common AEs

Asthenia

13 (3)

16 (3)

Dry mouth

7 (2)

16 (3)

Nausea

15 (4)

45 (9)

Dizziness

16 (4)

42 (8)

Somnolence

12 (3)

30 (6)

Paresthesia

6 (1)

21 (4)

Warm sensitation

7 (2)

21 (4)

Chest-related AEs

Chest tightness

2 (<1)

13 (3)

Chest pain

1 (<1)

1 (1 < 1)

Chest heaviness

0 (0)

1 (<1)

Chest pressure

1 (<1)

1 (<1)