From: Migraine is comorbid with multiple sclerosis and associated with a more symptomatic MS course
MS-NH | MS-Mig | p | |
---|---|---|---|
N | 73 | 94 | – |
Age in years (mean ± SD) | 47 ± 13 | 43 ± 11 | NS |
% Female* | 57% | 90% | <0.001 |
Disease duration in years (mean ± SD) | 13 ± 11 | 12 ± 11 | NS |
% Interferon beta-1 use | 71% | 64% | NS |
Co-existing conditions | |||
Hypertension | 12% | 15% | NS |
Diabetes | 0% | 4% | NS |
Seizures | 1% | 4% | NS |
Syncope | 1% | 7% | NS |
Thyroid disease | 8% | 10% | NS |
Fibromyalgia | 0% | 4% | NS |
Mononucleosis* | 5% | 20% | 0.006 |
Autoimmune disease | 4% | 12% | NS |
Bipolar disorder | 4% | 3% | NS |
Anxiety spectrum disorder | 8% | 16% | NS |
Depression | 21% | 36% | 0.028 |
Current smoker | 18% | 19% | NS |
Family history | |||
Family history of MS | 17% | 10% | NS |
Family history of migraine* | 19% | 49% | <0.001 |