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Table 1 Demographic characteristics, co-existing medical conditions and family history in MS-Mig and MS-NH groups

From: Migraine is comorbid with multiple sclerosis and associated with a more symptomatic MS course

  MS-NH MS-Mig p
N 73 94
Age in years (mean ± SD) 47 ± 13 43 ± 11 NS
% Female* 57% 90% <0.001
Disease duration in years (mean ± SD) 13 ± 11 12 ± 11 NS
% Interferon beta-1 use 71% 64% NS
Co-existing conditions
 Hypertension 12% 15% NS
 Diabetes 0% 4% NS
 Seizures 1% 4% NS
 Syncope 1% 7% NS
 Thyroid disease 8% 10% NS
 Fibromyalgia 0% 4% NS
 Mononucleosis* 5% 20% 0.006
 Autoimmune disease 4% 12% NS
 Bipolar disorder 4% 3% NS
 Anxiety spectrum disorder 8% 16% NS
 Depression 21% 36% 0.028
 Current smoker 18% 19% NS
Family history
 Family history of MS 17% 10% NS
 Family history of migraine* 19% 49% <0.001
  1. MS-Mig MS and migraine group, MS-NH MS–no headache group, NS non-significant
  2. p < 0.01