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Table 1 Demographic characteristics, co-existing medical conditions and family history in MS-Mig and MS-NH groups

From: Migraine is comorbid with multiple sclerosis and associated with a more symptomatic MS course

 

MS-NH

MS-Mig

p

N

73

94

Age in years (mean ± SD)

47 ± 13

43 ± 11

NS

% Female*

57%

90%

<0.001

Disease duration in years (mean ± SD)

13 ± 11

12 ± 11

NS

% Interferon beta-1 use

71%

64%

NS

Co-existing conditions

 Hypertension

12%

15%

NS

 Diabetes

0%

4%

NS

 Seizures

1%

4%

NS

 Syncope

1%

7%

NS

 Thyroid disease

8%

10%

NS

 Fibromyalgia

0%

4%

NS

 Mononucleosis*

5%

20%

0.006

 Autoimmune disease

4%

12%

NS

 Bipolar disorder

4%

3%

NS

 Anxiety spectrum disorder

8%

16%

NS

 Depression

21%

36%

0.028

 Current smoker

18%

19%

NS

Family history

 Family history of MS

17%

10%

NS

 Family history of migraine*

19%

49%

<0.001

  1. MS-Mig MS and migraine group, MS-NH MS–no headache group, NS non-significant
  2. p < 0.01