Skip to main content

Table 3 End points used in nine follow-up studies

From: Medication overuse headache: a critical review of end points in recent follow-up studies

Study, reference

Number of dropouts (%)

Headache days/month baseline

Duration of follow-up (months)

Headache days/month

Follow-up

Medication days/month baseline

Medication days/month follow-up

Response ratea

Number (%)

Relapse rate

Number (%)

2006 [20]

162/337 (48)

27

8

15e

–

–

67/337b (20)

–

2007 [21]

–

24.6

12

–

–

–

–

95/240 (39.6)

2007 [22]

22/106 (21)

26.1

12

11.5

–

–

–

–

2008 [23]

37/118 (31)

26.8

12

–

–

–

–

17/83 (20.5)

2009 [24]

5/61 (8)

24.1

12b

17.1e

23.2

8.0

14/41c (34)

–

2009 [25]

20/100 (20)

25.4

12

16.7e

–

–

27/93d (29)

16/80 (20)

2009 [26]

43/215 (20)

22.5

12

–

21.6

–

–

38/172 (22)

2009 [27]

36/93 (39)

26.2

12

12.0

–

–

–

–

2009 [15]

111/260 (43)

25.3

12

10.4

–

–

–

–

Number

8

9

9

6

2

1

3

4

Mean

29

25.3

11.6

13.8

–

–

28

25.5

  1. aCalculation of response rate (proportion of individuals with ≥50% reduction in headache frequency from baseline) differ between the three studies with respect to (a) number of participants included in the analysis and (b) time interval before evaluation
  2. bAnalysis of 337 participants (all included) evaluated after a mean of 8 months
  3. cAnalysis of 41 individuals evaluated after 12 months (20 controls excluded because of 5 months follow-up duration)
  4. dAnalysis of 93 individuals evaluated 3 months after withdrawal
  5. eTTH patients included
Back to article page

The Journal of Headache and Pain

ISSN: 1129-2377

Contact us