Table 6 Genotypic and allelic frequencies of 5-HT6 polymorphism in controls, migraine without aura and without drug overuse (MO) and medication overuse headache (MOH)
From: Lack of association between five serotonin metabolism-related genes and medication overuse headache
|  | Controls (n = 100) | MO (n = 84) | MOH (n = 99) |
|---|---|---|---|
5-HT6 (267) genotype | |||
 TT | 74 (0.74) | 55 (0.65) | 61 (0.62) |
 TC | 24 (0.24) | 26 (0.31) | 32 (0.32) |
 CC | 2 (0.02) | 3 (0.04) | 6 (0.06) |
MO versus controls | χ2 = 1.697 (P = 0.428) | ||
MOH versus controls | χ2 = 4.489 (P = 0.106) | ||
MOH versus MO | χ2 = 0.721 (P = 0.697) | ||
5-HT6 alleles | |||
 T | 172 (0.86) | 138 (0.84) | 154 (0.77) |
 C | 28 (0.14) | 26 (0.16) | 44 (0.23) |
MO versus controls | χ2 = 1.70 (P = 0.192) | ||
MOH versus controls | χ2 = 4.53 (P = 0.033)* | ||
MOH versus MO | χ2 = 0.56 (P = 0.456) | ||