Table 1 Analgesic and antihyperalgesic doses of indomethacin, prochlorperazine and caffeine as Indoprocaf, and sumatriptan
Analgesic doses from the literature (mg/kg) | Analgesic doses in the PTX experiment (mg/kg) | Antihyperalgesic doses (mg/kg) | Oral antimigraine doses in the clinical practice (mg) | |
|---|---|---|---|---|
Indomethacin | 1 [23] | 1 | 0.1 [7] | 25 [3] |
Prochlorperazine | 1–2 [13] | 1 | 0.1 [7] | 2 [3] |
Caffeine | 1–5 [15] | 3 | 0.3 [7] | 75 [3] |
Sumatriptan | 10–30 [21] | 20 | 1 [24] | 50 [3] |