Table 1 Migraine data and results of pain measurement in healthy controls and in migraine subjects presented as arithmetic mean and standard deviation; statistical comparison by Mann-Whitney-U-test with subsequent Bonferroni correction
Control (n = 20) | Migraine (n = 20) | ||
|---|---|---|---|
Migraine duration (years) | – | 9.9 ± 4.7 | |
Migraine frequency per month | – | 1.2 ± 2.2 | |
Peripheral (tibial) region stimulation | |||
Sensory threshold (mA) | 1.2 ± 0.6 | 1.1 ± 0.6 | ns (p = 0.60) |
Pain threshold (mA) | 7.0 ± 5.0 | 6.7 ± 4.8 | ns (p = 0.70) |
Threefold pain threshold stimulation (VAS in mm) | 2.6 ± 1.8 | 2.9 ± 1.8 | ns (p = 0.76) |
1. Train with 1.5-fold pain threshold stimulation (VAS in mm) | 2.9 ± 1.9 | 2.8 ± 1.8 | ns (p = 0.99) |
2. Train with 1.5-fold pain threshold stimulation (VAS in mm) | 3.0 ± 2.2 | 3.0 ± 1.6 | ns (p = 0.68) |
Difference between 2. train and 1. train | 0.1 ± 0.8 | 0.2 ± 1.0 | ns (p = 0.76) |
Trigeminal region stimulation | |||
Sensory threshold (mA) | 1.0 ± 0.5 | 1.0 ± 0.3 | ns (p = 0.76) |
Pain threshold (mA) | 3.6 ± 1.8 | 3.3 ± 2.0 | ns (p = 0.41) |
Threefold pain threshold stimulation (VAS in mm) | 3.8 ± 2.2 | 4.8 ± 1.6 | p = 0.04* |
1. Train with 1.5-fold pain threshold stimulation (VAS in mm) | 3.9 ± 2.3 | 4.1 ± 1.4 | ns (p = 0.29) |
2. Train with 1.5-fold pain threshold stimulation (VAS in mm) | 3.8 ± 2.4 | 4.3 ± 1.7 | ns (p = 0.33) |
Difference between 2. train and 1. train | −0.05 ± 1.2 | 0.2 ± 1.3 | p = 0.046* |