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Table 1 Literature review of co-occurrence of cluster headache (CH) and paroxysmal hemicrania (PH)

From: Coexistence of cluster headache and paroxysmal hemicrania: does it exist? A case report and literature review

Author

Age/sex

Features of CH

Features of PH

Interrelation between CH and PH

Treatments

Comments on diagnosis

Jotkowitz [1]

43 Y/M

f:1–3/day

d: 45–60 mts

f: 8/day

d: 20–30 mts

CH changed to PH after 4 years

Methysergide and ergot for CH

Indo For PH

Changed character of headache

(PH) satisfy the IHS criteria of CH

Pearce et al.

[2]

58 Y/M

f: daily

d: 30–120 mts

f:10–14/day

d: 5–40 mts

CH changed to PH after about 9–10 years

Ergot for CH

Partial relief by ergot in PH

Com. relief by Indo. in PH

Only 1 episode of PH (no recurrence after withdrawal of indo)a

Response by indo. in 22 days

Tehindrazanarivelo et al. [3]

Case 1

33 Y/M

f: 2/day

d: 120 mts

f: 20–30/day

d: 10–20 mts

Past history of CH

Recent attacks include both PH and CH

Verapamil for CH

Indo. for PH

Only 1 episode of PH (no recurrence after withdrawal of indo)a

Case 2

45 Y/M

f:2–3/day

d: 120 mts

f:15–30/day

d: 2–30 mts

Past history of CH

Recent attacks include both PH and CH

Verapamil for CH

Indo. for PH

Only 1 episode of PH (no recurrence after withdrawal of indo)a

Centonze et al. [4]

42 Y/M

f:2–3/day

d: 30–120 mts

f:8–16/day

d: 5–12 mts

Past history of CH

Recent attacks include both PH and CH

Verapamil for CH

Indo. for PH

Only 1 episode of PH (no recurrence after withdrawal of indo)a

Gobel et al.b [5]

47/M

b

b

b

b

b

  1. aAt least two attacks separated by pain-free remission periods of ≥1 month are required for IHS criteria of EPH
  2. bDetails not available
  3. com complete, d duration, f frequency, Indo Indomethacin, mts minutes, Y years