From: GERD prevalence in migraine patients and the implication for acute migraine treatment
Diagnosed GERD n = 403 | Diagnosed heartburn n = 212 | Symptoms of GERD or heartburn n = 290 | No GERD or heartburn symptoms n = 927 | P value | |
---|---|---|---|---|---|
Demographic characteristics | |||||
Age, mean (SD) | 43.9 (11.1)c | 42.1 (11.8) | 39.2 (11.5) | 40.3 (11.8) | 0.05 |
Female (%) | 69.5c | 67.0c | 75.9 | 75.1 | 0.02 |
College graduate (%) | 38.9 | 41.5 | 45.2 | 46.4 | |
Prescription drug insurance (%) | 88.6 | 86.3 | 83.8 | 88.8 | 0.08 |
Migraine characteristics | |||||
Age at diagnosis, mean (SD) | 28.3 (12.1) | 26.7 (11.5) | 27.2 (10.9) | 26.7 (10.6) | |
General migraine severity (%) | |||||
Mild | 1.7 | 1.4 | 2.8 | 3.5 | |
Moderate | 37.7 | 39.2 | 47.2 | 50.0 | |
Severe | 60.5c | 59.4c | 50.0 | 53.4 | 0.03 |
Attack frequency per montha, mean (SD) | 6.2 (6.3) | 6.7 (6.7)b | 5.1 (5.5) | 5.7 (6.1) | 0.05 |
Other primary headaches (%) | |||||
Tension | 80.9 | 84.4b | 79.7 | 76.5 | 0.04 |
Cluster | 36.5 | 40.6 | 37.2 | 35.0 | |
Chronic daily | 40.0c | 39.6c | 31.0 | 30.1 | 0.001 |
Sinus | 69.2 | 68.9 | 64.8 | 64.7 | |
Symptoms at headache onset (%) | |||||
Nausea | 63.0 | 58.5 | 60.3 | 55.5 | 0.06 |
Vomiting | 13.2 | 10.7 | 11.0 | 12.2 | |
Migraine provider type (%) | |||||
Neurologist/headache specialist | 25.6 | 22.2 | 16.5c | 24.2 | <0.01 |