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Table 5 Sum of pain intensity differences (SPID) and total pain relief (TOTPAR) in the 4-h observation period (intention-to-treat dataset)

From: Tolerability and efficacy of a combination of paracetamol and caffeine in the treatment of tension-type headache: a randomised, double-blind, double-dummy, cross-over study versus placebo and naproxen sodium

 

PCF

NAP

PLA

SPID

 n

91

91

91

 Baseline intensity (SE)

2.0 (0.06)

2.1 (0.07)

2.1 (0.08)

 Mean (SE)

4.0 (0.35)

4.2 (0.38)

2.1 (0.35)

TOTPAR

 n

81

81

81

 Mean (SE)

8.5 (0.60)

8.0 (0.63)

4.8 (0.60)

  1. PCF paracetamol 1,000 mg + caffeine 130 mg, NAP naproxen sodium 550 mg, PLA placebo